Cisco Identity Services Engine Injection Vulnerability
Cisco Identity Services Engine contains an injection vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC due to insufficient validation of user-supplied input allowing an attacker to exploit this vulnerability by submitting a crafted API request. Successful exploitation could allow an attacker to perform remote code execution and obtaining root privileges on an affected device.
A remote attacker, without authentication, can achieve full data confidentiality loss, arbitrary modification of data, complete denial of service or system unavailability. Federal agencies are required to remediate by 2025-08-18 under CISA BOD 22-01.
This is a Software Vulnerability (CWE-74) (CWE-74) vulnerability in Cisco Identity Services Engine. A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device. Exploitation requires remote network access, low attack complexity, no authentication required, and no user interaction required.
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Phishing link
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Malicious file
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Server compromised
Probably yes if any of these apply:
Active exploitation documented in the wild. Threat-research write-up: https://www.zerodayinitiative.com/blog/2025/7/24/cve-2025-20281-cisco-ise-api-unauthenticated-remote-code-execution-vulnerability
Manual remediation steps
Apply the Vendor Patch
This vulnerability is in the CISA Known Exploited Vulnerabilities catalog — apply the vendor's security update as soon as possible.
CISA required action: Apply mitigations per vendor instructions, follow applicable BOD 22-01 guidance for cloud services, or discontinue use of the product if mitigations are unavailable.
References
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References